Manufacturer: Parnell Laboratories (Aust) Pty Ltd Registered Name Sodaphos Injection for Cattle Composition Sodium acid phosphate 500 mg/mL. Actions Pharmacology Phosphate is involved in several metabolic functions including bone deposition, calcium metabolism, acid-base buffering, B vitamin utilisation and in enzyme systems. Dietary deficiency of phosphorus is widespread under natural conditions. Large areas of grazing land are of little value for livestock production without phosphorus supplementation. The phosphorus content of plants decreases with maturity. Phosphorus deficiency is most common in animals at pasture but can also be a problem in housed cattle fed on hay. Phosphorus requirements vary from 15 g daily for light cows to 40 to 50 g daily for heavily lactating cows. If the phosphorus intake is inadequate it may cause decreased appetite and milk production, poor growth and infertility and can be associated with parturient paresis. Hypophosphataemia may also result in haemolytic anaemia, thrombocytopenia, neuromuscular and CNS disorders, and osteodystrophies. Phosphate is eliminated via glomerular filtration but a large percentage of the administered dose undergoes tubular reabsorption. Indications Phosphorus deficiency in cattle. Contraindications Administration to animals with hyperphosphataemia, hypocalcaemia, hypernatraemia and oliguric renal failure. Precautions In areas of established phosphorus deficiency oral phosphorus supplementation should be provided. Disposal Dispose of empty container by wrapping with paper and putting in garbage. Dosage and Administration Adult cattle. Primary phosphorus deficiency. 20 to 40 g/animal (10 to 20 mL/100 kg bodyweight) daily for 1 to 3 days by subcutaneous injection. Phosphorus deficiency associated with parturient paresis. 30 g (60 mL) diluted in 240 mL Water for Injections BP, by intravenous injection. Specific therapy for the primary disease should be implemented concurrently.
