Manufacturer: Pfizer Animal Health
Registered Name Glanvac 3 Vaccine
Composition Multicomponent adjuvant vaccine containing ultrafiltered antigens of Corynebacterium pseudotuberculosis (ovis), Clostridium perfringens type D and Cl. tetani. The adjuvant, which is an aluminium salt, increases the level and duration of the immunity conferred by the vaccine.
Actions Immunity against the clostridial diseases covered by the vaccine develops about ten days after vaccination; the second dose, given four weeks after the first, should ensure a high level of immunity against these diseases. Immunity against caseous lymphadenitis develops within two weeks of administration of the second dose. To achieve maximum protection against caseous lymphadenitis, lambs and kids should be vaccinated before probable exposure to infection. Booster doses should preferably be timed to give best protection at times of maximum exposure, e.g. for caseous lymphadenitis, before shearing and dipping.
Indications Control of caseous lymphadenitis; prevention of enterotoxaemia (pulpy kidney disease) and tetanus in sheep, lambs, goats and kids. See product literature for further details. Always seek veterinary advice about the most suitable type of vaccine for use in a particular area.
Precautions Correct vaccination procedure in the field is important.
Avoid carcass damage. Use recommended injection sites. Animals should preferably be inoculated in temporary yards on clean grass, as shearing sheds and fixed mustering yards are likely to be heavily contaminated with clostridial spores. Avoid injection of animals during wet weather or under dusty conditions, as far as possible. Sterilise syringes and needles immediately before use by boiling in water for 10 minutes. Avoid use of strong disinfectants on apparatus.
Inject subcutaneously only, using the shortest possible needle not exceeding 15 mm in length.
Avoid secondary infection of injection sites. Maintain cleanliness at all times during vaccination. Take great care to avoid contamination of the vaccine, needle and internal parts of the syringe by contact with unsterile surfaces or unwashed hands. Keep needles sharp and clean and replace frequently.
Clean the proposed site of inoculation on the animal's skin by swabbing with cotton wool soaked in an antiseptic solution, such as methylated spirits.
It is important that the vaccine is kept properly mixed before and during use.
Do not inject at any other site than that recommended.
Unused vaccine may be held over for use the next day, provided instructions for resealing are carried out. See carton for resealing instructions.
Disposal. Dispose of empty containers by putting in garbage. Discarded needles should be immediately placed into a designated and appropriately labelled sharps container.
Withholding Periods Meat. Nil. Milk. Nil.
Adverse Reactions Localised swelling may develop at the site of injection and a firm nodular lump may persist for some weeks or even months.
Cases have been recorded of goats developing signs of anaphylactoid shock shortly after vaccination. This is believed to be due to protein sensitisation as a result of previous vaccination. This vaccine has been prepared in a manner which will reduce the risk as far as possible. Nevertheless, observe valuable animals closely for one hour after vaccination. Obtain veterinary assistance immediately if signs of shock become evident.
Dosage and Administration Inject subcutaneously on the side of the neck (just behind and below the base of the ear).
Sheep, goats. All ages, 1 mL; repeat four weeks later. Do not give first dose to lambs less than 3 weeks old; young lambs are less likely to develop protective immunity to CLA. Give a 1 mL booster dose 12 months after the two basic doses to confer lifelong immunity against tetanus, but not necessarily against enterotoxaemia (pulpy kidney disease) or caseous lymphadenitis; give all animals annual booster doses to control caseous lymphadenitis. Goats require regular revaccination at six monthly intervals to maintain effective immunity against enterotoxaemia. Sheep will require annual or more frequent booster doses to maintain effective immunity against enterotoxaemia in high risk areas. Where possible give booster doses prior to the time of maximum risk, e.g. transfer to lush pasture or grain feeding in the case of enterotoxaemia.
Pregnant ewes and does. Give previously unvaccinated animals 1 mL at the time of mating; repeat at up to four weeks before the expected date of birth. Omit the dose at time of mating in previously vaccinated animals.
Vaccinated pregnant ewes and does will pass on immunity to their lambs and kids in the colostrum. Lambs and kids should be protected for the first six to eight weeks of their lives. In heavily CLA infected flocks, maternally derived immunity may interfere with response of lambs to vaccination against CLA before 10 weeks of age.
Presentation Injection (plastic pack): 100 mL, 250 mL, 500 mL.
Storage Store at 2 to 8 deg. C. (Refrigerate. Do not freeze.) Protect from light.
