Manufacturer: Pfizer Animal Health
Registered Name Ultravac 7 in 1 Vaccine
Composition Prepared from formalin-killed cultures of Leptospira borgpetersenii serovar hardjo type Hardjobovis and L. interrogans serovar pomona, an antigenically balanced mixture of ultrafiltered antigens of Clostridium perfringens type D, Cl. tetani, Cl. septicum and Cl. novyi type B and a purified formol culture of Cl. chauvoei. It is adjuvanted with an aluminium salt to increase the level and duration of immunity.
Actions The purification procedures used ensure maximum protection of stock with minimum risk of local reaction at the injection site. Detectable antibody develops ten to 14 days after vaccination. The second dose four to six weeks after the first is essential before a high level of immunity can develop.
Indications Prevention of enterotoxaemia (pulpy kidney disease), tetanus, black disease, malignant oedema (blackleg-like disease), blackleg and leptospirosis in cattle.
Prevention of urinary shedding of the named leptospires in cattle when used prior to natural exposure. Prevention of the risk of human leptospiral infection associated with shedding of the named leptospires in the urine and from the reproductive tract of cattle.
Prevention of reproductive tract colonisation and placental and foetal infection with L. hardjo.
Precautions Correct vaccination procedure in the field is important.
Avoid carcass damage. Sterilise all injection apparatus by boiling in water for ten minutes (or equivalent). Avoid use of strong disinfectants on apparatus. Maintain cleanliness at all times during vaccination. Take great care to avoid contamination of the vaccine, needle and internal parts of the syringe by contact with unsterile surfaces or unwashed hands. Keep needles sharp and clean, and replace frequently. Use the shortest possible needle not exceeding 15 mm in length. As far as possible, avoid injection of animals during wet weather or under dusty conditions. Inject subcutaneously only. If possible, inject high on the side of the neck behind the ear.
Before injecting the vaccine, clean the proposed site of inoculation on the animal's skin by swabbing with cotton wool soaked in an antiseptic solution, such as methylated spirits. Unused vaccine may be held over for use the next day, provided instructions for resealing are carried out.
Shake well before use and keep thoroughly mixed during use. It is important that the vaccine is kept properly mixed before and during use.
Disposal Dispose of empty containers by wrapping with paper and putting in garbage. Discarded needles should be immediately placed into a designated and appropriately labelled sharps container.
Withholding Periods Nil.
Adverse Reactions Some swelling usually develops at the site of injection, and may last for some months before gradually subsiding. On rare occasions, allergic shock reactions have occurred. In these cases adrenaline should be administered. A veterinarian should be contacted regarding the use of adrenaline.
Dosage and Administration The dose on all occasions is 2.5 mL injected subcutaneously (just under the skin) high on the side of the neck, if possible.
Herd vaccination. To begin a herd vaccination program, all animals must be vaccinated and a second dose given four to six weeks later. An annual booster dose of vaccine must be given. This program is applicable to dairy and beef herds.
Vaccination of calves. Early vaccination of calves is advisable to protect against acute leptospirosis (‘redwater’) and also to minimise the risk of animals acquiring infection and thus becoming carriers prior to vaccination. Calves may be first vaccinated from 1 month of age.
Two doses should be given, four to six weeks apart. Calves less than 3 months of age at the time of the second vaccination should receive a single booster dose six months later. This booster may be used to align calves vaccinated out of season (i.e. when young, or in a town supply herd) with the annual herd booster.
Introduced stock. In the absence of a known history of vaccination, dose twice at a four to six week interval. It should be kept in mind that those introduced animals already infected with leptospirosis may still excrete leptospires after vaccination and may require concurrent treatment with antibiotics.
Booster doses. To maintain immunity, all animals in the herd, including steers and bulls, should be revaccinated annually against leptospirosis. Breeding females should be given their annual booster about one month before calving or at drying off. In this way not only will they be protected, but they will pass on temporary immunity to their offspring in their colostrum or first milk. A booster dose of a suitable multicomponent vaccine given twelve months after the two basic doses of vaccine should confer lifelong immunity against tetanus and blackleg. To maintain effective immunity against black disease, annual booster doses of a suitable multicomponent vaccine should be given.
The two basic doses of Ultravac 7 in 1 should provide effective immunity against enterotoxaemia for three months. Booster doses are therefore necessary to maintain immunity against enterotoxaemia in cattle and should be given at appropriate intervals according to local and seasonal conditions.
Please add vaccine surcharge from the Freight Section to your order so refrigerated vaccine can be sent. Not available for orders outside of Australia.